?MALARIA IN THE DUARS. I.-INTRODUCTION. It is a very common assumption that, just as an epidemic outbreak of malaria must, it is thought, be due to some unusual prevalence of anopheles or to the introduction of some species especially favouring the transmission of the disease, so an intensely malarious area must be so by reason of the existence of special facilities for the breeding of anopheles, or the presence of particularly dangerous species. Under such an assumption the prevalence of malaria in the Duars might be put down to the particular physical features of this country especially favouring the breeding of anopheles, or to the existence of a particular species, M. listoni, a species which it was suggested by the Royal Socěety's Commission might be a factor in bringing about a condětěon of intense malaria. But the facts given in the body of this report suggest that the extraorděnary prevalence of malaria in the Duars-for we may state without going into details that we found malaria extraordinarily pre- valent and peculiarly intense throughout the whole area-is not solely, or even maěnly, the result of special facilities for the breeding of ano- pheles, or of the existence of a partěcular species, but on the contrary is bound up in what we shall call the "human factor," an increased or diminished supply of anopheles, so long as there are any at all present, appearing to exert little or no influence upon the prevalence of the disease. The Duars, with its 150,000 immigrant coolies aggregated in its numerous labour camps, is an example on a great scale of conditions that in our experience are practically always associated with an extra- ordinary prevalence of malaria. These conditions, though hitherto they have not been recognised in their bearing upon malaria, are nevertheless very distinct and important. They may, speaking ISC A