?(81)
The plan of giving only one dose of 15 grains once a week merits further
trial, as it is obvious that the best plan of dosage is that which effects the
desired result with the least expenditure of quinine and at the least cost of
time and trouble.
Good results have been reported from the use of each of the methods, and
it is the duty of the officer in charge of the persons who are to be treated
prophylactically to choose one of the plans, having regard to local circum
stances and to the degree of control which can be exercised during the prepara-
tion and administration of the prophylactic doses, and to abide by it. The
decision having been made, the next consideration will be the administrative
details connected with the proper carrying out of the measure. The dates
between which the method will be undertaken will be decided and then the
details of the procedure to be followed. Printed forms may be used in which
these details can be entered each time the prophylactic doses are given. The
forms might contain the following headings:-
Name of Jail or Institution.
Date of administration of the prophylactic.
Number of persons to whom the prophylactic was administered.
Drug and dose in grains.
Form in which the drug was administered.
Name of the person who made up the prescription. What precautions were
taken to ensure that it was correctly dispensed ?
Name of the person who administered the prophylactic. What precautions
were taken to ensure that it was correctly administered to all for
whom it was intended ?
General remarks.
It must always be borne in mind that the results obtained in the preven-
tion of malarial fevers by the use of quinine are dependent entirely upon the
degree of supervision exercised during the preparation and during the adminis-
tration of the doses, and that in institutions where this method of prophylaxis
is adopted the prevalence of malarial fevers among the inmates is one measure
of the care and capacity with which the duties of management are performed.
In order to illustrate the minute attention to details which is essential
for obtaining successful results in prophylaxis by the use of quinine the
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