3
bability, that Cholera does not exist in them as an endemic, it cannot be formally
concluded that it does not.
" Question 3rd.-Is there not reason to fear that Cholera may become natura-
lized in our (European, &c.) countries ?
" Answer.-It appears likely that by repeated invasions, the principle of the
disease may in some manner be naturalized.
" Question 4th.-Is there in the Hijaz an original source of Cholera, either
permanent or periodic ?
" Answer.-Asiatic Cholera does not appear to have an original source in the
Hijaz, but it appears to have been hitherto always imported there.
" Question 5th.-Are there certain localities in India where alone Cholera is
engendered, or which are particularly favorable to its development? In other words,
is Cholera endemic in all parts of India, or only in certain districts, which it is possible
to circumscribe ?
" Answer.-There are in India certain localities, chiefly in the valley of the
Ganges, where Cholera is endemic, without its being possible to particularize all, or to
affirm that they exclusively give birth to the disease.
" Question 6th.-Do we know the concurrence of causes under which Cholera
has its spontaneous birth in India ; also the circumstances which make it take an
epidemic form ?
" Answer.-We do not know the special conditions under which Cholera has
its birth in India and reigns there endemically in certain localities.
" Question 7th.-What are the circumstances that conduce to the develop-
ment and propagation of epidemics of cholera in India ?
" Answer.-Pilgrimages are in India the most powerful of all the causes
which conduce to the development and to the propagation of epidemics of cholera.
" Question 8th.-Is the transmissibility of cholera now proved by facts that
admit of no other interpretation ?
"Answer.-All the facts hitherto ascertained demonstrate that Cholera is
propagated by man and with a speed proportioned to the amount and rapidity of his
emigrations. The transmissibility of Asiatic Cholera is incontestable, and is proved
by facts that admit of no other interpretation.
"Question 9th.-Are there any conclusive facts that constrain us to admit
that cholera can be spread to a distance by certain conditions of the atmosphere, by
winds, or any other change or modification of the air ?
"Answer.-Hitherto no fact has proved that cholera can spread to a dis-
tance by the atmosphere alone, whatever may be its condition.
"Question 10th.-How is cholera imported, and what are the agents in its
transmission ?
"Answer.-From all that has been learnt, there are two things necessary to
the outbreak and the spread of Asiatic Cholera in a locality-an arrival from an infected
place and circumstances that favor the transmission. As regards the former, an 
arri-