?1O persons who were exposed to infection in places where plague was at its height, and many persons who were already incubating plague were unavoidably operated upon. No information was secured as to the maximum duration of the protection afforded, but statistics were compiled with reference to a considerable number of persons showing the number of days which intervened between their inoculation and attack and the results of their attacks, and these statistics indicate that some protection was afforded immediately after inoculation, that the protective value of the operation increased up to three months from the date of inoculation, and that it lasted even after three months. That the duration of protection is considerable is evidenced by the facts already mentioned above regarding the influence on plague in 1901 exercised in Jullundur and Hoshiárpur by inocula- tions performed during the hot weather of 1900. It should be noticed here that in the course of all the operations mentioned above no accidents due to the use of bad fluid came to light. Had there been any such accident it is certain that it would have been reported, since rumours of the dangers of inoculation were prevalant and all minor accidents due to it were brought to the notice of the Medical Officers concerned and in many cases exaggerated. Such minor accidents consisted mainly of the formation in a few cases of abscesses at the seat of inoculation. In one or two cases it was alleged that death had followed the operation, but in all these cases it was clearly proved that the deaths were due to plague contracted before inoculation. Any harm caused by the operation or any reason to belief that it was prejudicial would certainly have been brought to light. Everywhere, however, the impression of all officers who had experience of the results of inoculation was very strongly in its favour, and the people when not already convinced of its value were open to conviction if a strong effort to press inoculation upon them should be made. In Ambala, Ferozepore and Gurdáspur inoculation appeared to be in demand, as it was in Jullundur, where it was done only on a written application for it ; in Hoshiárpur and Ludhiána the people were willing to resort to it when plague was severe ; in Siálkot the people were beginning to understand its advantages ; and in Lahore also it was remarked that the people would accept it if they were pressed to do so. 22. Sir Charles Rivaz had before him in the hot weather of 1902 reports and statistics which put him in possession of the main facts set forth in the preceding paragraph. Therefore when he considered how Government could with the greatest hope of success assist the people to combat the outbreak of 1902-03, which he feared would be very severe and widespread, he turned to inoculation. Other plague measures had failed ; Government was not in a position to enforce them, and the people were not ready to combine for their effective adoption ; inoculation was a measure which offered individuals a chance of protecting themselves even in the absence of combined action ; there was no other measure by which individuals could so protect themselves ; and there was good reason to believe that very large numbers would accept without compulsion inoculation if Government advised them to resort to it and provided them with adequate facilities for doing so. It was anticipated that inoculation would restrain plague in the Punjab and decrease the risk of its spread to other parts of India, and it was believed that it would avert plague attacks from numbers who would otherwise fall victims to the disease and would save the lives of numbers even if they were attacked. It was not expected that inoculation would at once stamp out plague, but it was hoped that the success of the operations in 1902-03 would render it increasingly easy to deal with outbreaks in succeeding years, and would confine those outbreaks to constantly narrowing limits. The Lieutenant-Governor, however, felt that no scheme would be adequate which did not make it possible to inoculate in advance of plague at least two-thirds oí the population of the 13 districts in which the disease had taken its firmest hold. It was calculated that for a scheme of this magnitude 70,000 doses of prophylactic fluid would be required daily during the period of the operations. The only existing source of supply was the Plague Research Laboratory at Bombay" and before any other action was taken the Laboratory authorities were asked if they could supply the required amount. On the 17th of June the Laboratory authorities gave an assurance that the amount could be supplied and that special arrangements