?10 Method of its performance. Records. 22. The method of performing the operation calls for no description here. The records concerning inoculation were similar to those described in the reports on inoculation for 1899-1900. though it should be stated that (c)wing partly to the relative weakness of the staff and partly to the conditions which have been referred to in dealing with the leading information, it is not possible to attain or maintain as complete records concerning inoculation as in former years. Effects of inoculation. 23. From what has been stated above it will be evident that the statistical evi- dence of the value of inoculation during the year under report is very incomplete. In only very few instances were data obtainable for comparing the incidence of out- breaks of plague upon inoculated or uninoculated communities living under otherwise similar conditions. A comparison based upon the total figure of the Province would be of no value, because on the one hand in some districts only isolated cases of plague occurred among large populations, and in the others a large number of inoculations were performed after outbreaks of plague had ceased. Such data as were obtained are dealt with in the reports of the districts concerned, but it may be said here that in nearly every instance inoculated communities suffered much less severely from plague than the unin- oculated. The number of attacks and deaths among inoculated persons are shown in State- ments 1 (Appendix A) and 9 (Appendix B) in the latter of which the number and fatality of attacks at varying periods after inoculation are shown. In Statement No. I it is shown that of the 235,776 persons inoculated in the British districts, 881 were attacked with plague, of whom 309 died. The figures are included in those of the total number of cases and deaths from which they must be deducted to show the number of cases and deaths among uninoculated persons. These amounted to 266,700 and 173,732 respectively. The fatality of attack among the uninoculated was 65.14 and among the inoculated 35.07. Attention may be drawn here to the remarks made by several officers that although plague occurrences among uninoculated persons may have been concealed, the people promptly brought to light all such occurrences among the inoculated. However doubtful therefore the value of the statistics concerning plague occurrences may be, there seems little room for doubting that the figures showing the fatality of attacks among the inoculated are fairly correct, and unless it be held that the number of unreported cases of plague among the uninoculated was so great as to materially reduce the figure showing the fatality of attacks among this class, that the inoculated persons who were attacked with plague had nearly twice as great a chance of recovery than the uninoculated. Should it be held that a very large number of cases among uninoculated persons were concealed, the comparison of the incidence of plague attacks among uninoculated and inoculated becomes more unfavourable to the former. In Statement No. 9 (Appendix B) the 881 cases of plague among inoculated persons are shown according to the period which elapsed between inoculation and attack. The figures shown for each period in different districts are often too small to be of much value, but when grouped are sufficiently large to permit of comparison being made between them. It will be seen that though the figures for different districts vary considerably, the fatality of attacks among the inoculated is much less at all periods except during the first week after inoculation than among the uninoculated in every district, and that taking the figures for all districts together attacks even during the first week after inoculation were slightly less fatal than attacks among uninoculated persons. It would appear from the statement that the protective value of inoculation against death from plague increases up to three months and then declines, though even after four months the inoculated are better off than the uninoculated. Infection. Manner in which the infection of plague is con- veyed. Human agency. 24. All officers, Civil and Medical, were convinced that plague is almost invariably conveyed from one place to another by human intercourse, either directly by persons suffer- ing from the disease or indirectly in infected clothing and bedding or other personal effects. Rats. The only other possible carrier of infection mentioned in the district reports is the rat, and the instances in which it appeared more probable that villages had been infected by rats than that the disease had been introduced by human agency were very few. The statements made in the reports of most badly-infected districts that in many villages rats died before any human beings were attacked cannot be taken as conclusive evidence that infection was introduced by rats because it has to be considered along with the equally prevalent statements in the reports of district officers that the earlier cases of outbreak were usually concealed. From the facts recorded in certain reports of the migration of rats from infected to uninfected villages, there can, however, be little doubt that these animals do occasion- ally introduce the infection of plague into previously uninfected villages.