?No. 836S., dated Shillong, the 16th July 1897. From-Surgeon-Colonel A. STEPHEN, M.B., Principal Medical Officer and Sanitary Commissioner, Assam, To-The Secretary to the Chief Commissioner of Assam. I have the honour to forward Surgeon-Captain Rogers' report on his investigation into kála-azár in Assam, with the following remarks. 2. Before proceeding to Assam to commence his enquiry into this disease, Dr. Rogers spent a few days in Calcutta, in order to study the literature of kála-azár and allied subjects available at that place. Leaving Calcutta on the 16th of April 1896, he visited Dhubri, Gauháti, Shillong and Tezpur, in order to learn the views of the Civil Surgeons of those places on the disease which he was about to investigate, and, on the 27th of that month, he arrived at Nowgong, the capital of the district in which the disease was at that time most prevalent, and which he was requested to consider as, for the time being, his headquarters. He spent the next five months in the Nowgong district in investigating the disease. During these months he studied the cases of the disease which he met in the Nowgong dispensary and jail, and in a large number of infected places in that district, including a considerable number of tea gardens. In October he proceeded to Shillong, in order to study the minute pathology of the organs of persons who had died of kála-azár in the Nowgong district, and on whom he had performed post-mortem examinations. He afterwards visited Sylhet to study cases of ordinary chronic malarial fever there, and to notice the differences, if any, between them and kála-azár. After leaving Sylhet, he paid a short visit to the Gáro Hills, and then made tours in the Nowgong district, in the Mangaldai and Tezpur subdivisions of the Darrang district, and in the Golághát subdivision of the Sibságar district, and in March 1897 he proceeded to Shillong to complete his report. 3. In the first section of his report, Dr. Rogers gives a short history of kála-azár. The disease was first described in the Assam Sanitary Report for 1882, in an appendix to which it is stated that the attention of administrative officers became directed to it in the Gáro Hills as far back as 1869. The disease gradually spread up the Brahmaputra river, especially on its south bank, and, when Dr. Rogers commenced his investigations, it had reached the eastern portion of the Nowgong district, and was beginning to make its appearance in the Bishnath portion of the Darrang district. Dr. Rogers points out that for several years, after the disease was first described in 1882, medical officers were of opinion that kála-azár was of malarial origin, and that it was not contagious. In 1889, Dr. Giles was appointed to enquire into, and report on, the cause or causes of kála-azár and beri-beri of Ceylon, and in October 1890 he published his report. In this report he gave it as his opinion that the increased mortality in the districts invaded by so-called kála-azár was due to anchylostomiasis. It was afterwards ascertained, especially through the investigations of Dr. Dobson, that anchylostoma were found in the majority of healthy people in Assam, and that the worm was present in persons not suffering from kála-azár in as great numbers as in those affected with that disease. At the time when Dr. Rogers was appointed to enquire into the nature of kála-azár, the majority of medical officers were of opinion that the disease in most respects resembled chronic malarial fever, but, as there seemed to be evidence that it was contagious, they considered that there might be some other factor in it besides malaria. All medical officers, with one exception, believed that the disease was quite distinct from anchylostomiasis. 4. In the third section of his Report, Dr. Rogers gives a clinical description of kála- azár. He defines it as a chronic and relapsing form of fever of an intermittent or irregularly remittent type, very resistent to treatment, producing progressive anćmia, great wasting, and, in many cases, dropsy, and terminating either in a final attack of fever or in asthenia, often accompanied by diarrhœa or lung complications. He states that the disease usually attacks several members of a household, and spreads slowly in a wave of increased fever mortality, and dies out in about six years from its com- mencement. He is of opinion that the disease may last from two months to three years, and that its usual duration is from four to nine months. From what he saw on tea gardens, he came to the conclusion that the number of cases begins to increase in April, that the disease is most prevalent during May, June and July, and that the months of minimum prevalence are December, January and February. He states that this seasonal incidence agrees closely with that of ordinary malarial fevers, except that it is more