?CHAP. II.] its causes and characteristics. 17 Difficulties in diagnosing the disease experienced in Bombay. In the report prepared by Mr. Snow, the Municipal Commissioner of the City of Bombay, the following remarks are made with regard to the difficulty experienced in diagnosing plague: "The difficulty of accurately diagnosing this multiform disease is admittedly very great; many suspicious cases were put down as diphtheria; the resemblance to enteric often made the differential diagnosis exceedingly difficult in the absence of bacteriological examination; and even bacteriological examination not infrequently proved abortive in clear cases of the plague. The disease in its more infectious type was generally pneumonic and devoid of glandular enlargements, or was wont to take the form of high fever with slight cough. Doctors often differed in their opinions about cases, and no clearer illustration of the difficulties of diagnosis can be given than the fact that at the latest stages of the epidemic numbers of cases had to be segregated-and that by medical officers- not because the patients had plague, but because they had suspicious symptoms." Dr. McCabe Dallas, who was in charge of the Grant Road Plague Hospital in Bombay, stated that during the early months of the epidemic the pulmonary form of the disease escaped detection and thus spread the infection unchecked. Dr. Bitter also noticed the difficulty of diagnosing pneumonic cases by clinical symptoms. Cases diagnosed as plague which are really unconnected with that disease. The experience of the City of Bombay illustrates how plague may escape detection at the beginning of an epidemic. On the other hand, when the alarm of plague has been raised, cases are often diagnosed as plague which are really unconnected with that disease. On a number of occasions reports were made to the Government of India of the occurrence of plague cases in different parts of India which subse- quently were found not to be true cases of plague. Instance from Calcutta. The most important instance occurred in the city of Calcutta. Early in October 1896, that is to say, shortly after the existence of plague in Bombay had been ascertained, the occurrence of ten cases in Calcutta and one in Howrah affirmed to be plague was reported by medical officers to the Special Medical Board appointed by the Government of Bengal. Considerable alarm was experienced, but after sifting the evidence the Medical Board were able to report* that these eleven cases were not true cases of plague, but simple cases of enlarged glands, fever, bronchitis, and venereal disease. They stated that looking only to the clinical symptoms they had no hesita- tion in expressing their emphatic opinion that none of the cases could properly be described as cases of bubonic plague. * Appendix I. 3