?CHAP. II.] its causes and characteristics. 27 These laboratory experiments not conclusive as demonstrating the loss of vitality in the bacillus. But the Government of India were advised that these laboratory experiments, though they may demonstrate the loss of pathogenic property, are inconclusive as demonstrating the loss of vitality in the bacillus, which might quite conceivably, although non-pathogenic at the time of the final experiments, again become pathogenic under favourable local conditions. Experience pointing to conservation of vitality. Example from Wetljanka. Dr. Bitter remarks that it seems probable that in a moist condition the bacillus may retain its vitality for a considerable time in surround- ings favourable to its life, such as contaminated clothing or bedding, and experience favours this view. Hirsch recites an example from the epidemic at Wetljanka in 1878-79. There was a girl of ten years of age in the house of whose parents a box of clothing had been deposited, coming from a house in which all the inhabitants had died two months previously. The girl opened the box, which up to that time had remained untouched and was about to be burnt. She took a piece of clothing out and set to work on it, and four days later, the epidemic having disappeared, the first symptoms of the disease showed themselves in her. Instance on a liner during the Bombay epidemic. Another interesting instance occurred on board a liner during the Bombay epidemic. The vessel embarked her crew at Bombay on the 20th August and anchored in the Thames on the 11th September. There were from three to four hundred passengers on board, and during the voyage there was no suspicion of plague among them or among the crew. On the 26th or 27th September one of the Indian Portuguese stewards fell ill and died on the 3rd October. Clinical and bac- teriological evidence pointed to plague. Another of the stewards who slept in the same cabin as the first was also taken ill about the 26th September and died on the 27th before he could be removed to hospital. The result of a careful enquiry was to the effect that the infection was derived from clothing contained in bundles which remained unopened until the end of the voyage. Action of chemical disinfectants. Both the German Plague Commission and Mr. Hankin made experi- ments to test the action of chemical disinfectants on the plague bacillus. The following is a summary of the conclusions of the German Commission:- Experiments of the German Commission. "A solution of corrosive sublimate of the strength of 1:1,000 killed the bacilli at once. Carbolic acid or lysol of the strength of 1 in 100 killed the bacilli within 10 minutes. When suspensions of the bacilli were treated with soft soap (3 in 100) or chloride of lime (1 in 100), they were found after 5 minutes still to contain virulent bacilli, but in 15 minutes sterility had been produced by the chloride of lime, and in 30 minutes by the soap. Sterilised fæces copiously infected with plague bacilli, and then mixed with equal parts of ordinary milk of