?86 Previous history of plague in India. [ CHAP. IV. thirst. Eyes commonly heavy and hazy; often bloodshot. Counte- nance in all the severer cases expressive of much anxiety and suffer- ing. Respiration generally easy, excepting in patients having inflammation of the lungs as the prominent feature of their malady. "Buboes appear in the groins, armpits and neck (usually on the left side), sometimes almost simultaneously with the fever, but more commonly in the course of the first or second day-rarely so late as the third or fourth. They are at first of small size, moveable, and always acutely painful to the touch. In some few cases they increase rapidly in bulk, suppurate, and discharge pus alone, or mixed with shreds of dead cellular membrane. In by far the greater number of instances, however, they do not become larger than a walnut, and show no disposition to suppurate. The groins are the situations in which the buboes appear most frequently. "Sometimes there is one in each groin, sometimes in one groin and one axilla, sometimes in one or both axilla and neck, in one or both groins and neck, or in the neck alone. Suppuration and even rapid increase of size without suppuration have been remarked by the Pali people to be favourable symptoms. In persons who recover from the disease, the buboes most frequently disappear gradually of their own accord. I saw one man, however, in whom a bubo, in the left groin, had attained a great size, and was likely to prove very troublesome. It extended from the pubis to near the anterior sup- erior spinous process of the ilium, and was hard and painful. In this patient the fever had ceased four days before I saw him. In this disease a remission of the febrile symptoms, more or less marked, takes place towards morning, the remission being of longer or shorter duration according to the mildness or severity of the malady in each individual case. In the worst cases there is no perceptible remission. In some the disease was so mild that the patients walked without assistance from their houses to the place where I was standing, had their buboes, pulses, etc., examined, swallowed their medicine and walked home again. In others, again, syncope followed any attempt to raise them from their charpoys. The head is but rarely affected in the early stages of the disease. Most of the persons I saw answered questions readily and distinctly. In fatal cases the patients become comatose some hours before death. "In a small proportion of cases inflammation of the lungs comes on, on the first or second day of the disease. The patient complains of acute pain of one or other side or behind the sternum; great difficulty of breathing; short dry cough; usually on the second or third day a small quantity (rarely more than half an ounce) of florid blood, in small coagula, is expectorated. In such cases buboes are