?110 Extent and course of the plague [ CHAP. V. the remainder spread over twenty-two of the thirty-two quarters into which the city is divided. The actual number of cases which occur- red during the week was, it is known, much greater than the number reported. Bearing in mind the slow rate at which the infection of plague spreads during the early period of an epidemic, it is certain that the disease must have been in existence for a considerable time before the cases could have become so numerous and so widely diffused. Cause of the outbreak. The immediate cause of the outbreak must remain a matter of con- jecture. It would seem probable that the infection was introduced by sea, since it is most unlikely that the disease could have been carried overland from the small endemic centre in the Himalayas, or that it could have been introduced from beyond the border by any land route. It has been seen that an endemic plague centre exists on either side of the Indian Peninsula-to the west in Mesopo- tamia and to the east in China. In so far as is known, there was no unusual prevalence of plague in Mesopotamia at the time of the out- break in Bombay. But on the west the second or 1896 outbreak in Hong-kong had not died out when Bombay became infected. The probability would therefore seem to point to China rather than to Mesopotamia as the source whence the infection was derived. In connection with this question it is interesting to note that Staff Surgeon Wilm, whilst eulogising the general arrangements made in Hong-kong to stamp out the epidemic, remarked that too little attention was paid to the water-borne traffic. And in India quarantine was not imposed against Hong-kong during the 1896 epidemic at that place, although it was imposed during the more important epidemic of 1894 and withdrawn when that epidemic ceased. Intimation of the recrudescence in 1896 was not sent to the Government of India, and it would appear that in Egypt also quaran- tine was not imposed. It is therefore quite possible that undetected cases of plague may have arrived from Hong-kong. Abnormal climatic condi- tions. The outbreak of plague in Bombay occurred at a time of unusual climatic conditions. The early cessation of the monsoon of 1896 is notorious in connection with the widespread famine which resulted in India. Dr. Weir has given the following account of the pheno- menon as it affected the City of Bombay:- " The mean annual temperature of the year was 80·7, the second highest on record in the last 51 years. The total fall of rain amounted to 87.6 inches, being 15 inches above the average. But the distri- bution of the rainfall was abnormal, for, instead of being distributed over four months, it was distributed over a much shorter period-a