?25 causes are usually at work, as in the case of a grain godown customarily used for the storage of grain brought from a place which is perennially infected. 6. It is unfortunate that no accurate record exists for any town in this Presidency of the genesis and history of the plague epidemics which have afflicted it, nor has any special attention been directed to the loca- lities and buildings in which the outbreaks began, or to the sources from which infection has been imported. Yet these factors should be well known to the local authorities, and should be the very foundation of their preventive policy. Recent inquiries have, for example, elicited the following facts :- (a) Salem district is regularly infected from the Mysore State through Hosur, and once plague appears in that town, it is a matter of a few weeks or even days for it to make its appearance in Salem town itself. (b) In Coimbatore town, Uppilipalaiyam and the weavers' and chucklers' quarters are well-known foci of infection from which plague spreads year by year, and the town itself is periodically infected from Mysore State or from South Kanara. 7. It is obvious that preventive measures which ignore fundamental factors of the kind can have little practical value. It is a needless extravagance, for instance, to attempt to destroy the rat population of a whole town instead of concentrating effort on the localities where the rat population is most dense, or where grain or cotton from areas known to be infected is habitually stored. Until exact information is on record for every town which is subject to epidemics, as to the foci and channels of plague infection, the preventive staff is groping in the dark. 8. The first duty of a health staff is therefore that of investigation. To illustrate the kind of investigation needed, plague mortality figures for the five towns, Bellary, Coimbatore, Salem, Mangalore and Vaniyambadi, have been collected for the twenty years, 1902-21, and graphs have been prepared (attached to this memorandum), showing the average monthly mortality in each. The first group demonstrates the seasonal prevalence which plague exhibits everywhere. The second group of graphs gives the actual deaths by months for the same period, and illustrate the irregularity with which epidemics have appeared in the towns in question. While perfect accuracy cannot be claimed for the figures on which they are based, the graphs prove the need for ascertaining why plague should break out in a given year and reappear at irregular intervals of two, three or more years. There must be some reasons for these irregularly occurring recrudescences and it is only by intensive inquiry that the causes can be ascertained. 9. Experience proves that in towns and villages susceptible to epidemics, infection usually spreads from grain dealers' stores, cloth bazaars and petty shops which afford special facilities in the form of food and shelter for the multiplication of rats. The first duty of a local health authority is therefore to compile an accurate record of the following points:- (a) the location, method of construction of granaries for trade as well as for household purposes, and their relation to the course of epidemics, 4