REPORT BY SURGEON-CAPTAIN J. F. EVANS.                          219

                                Experiment No. 37, Nepal charas, Shahjahani.

Yellow and white female cat, weight 4 lb 63/4 oz. Dose .25 grain at 2 P.M. Effect nil.

Satisfactory results having been obtained from the standard minimum dose in the case
of eight samples of hemp drugs, the next step was to test what quantity of the other samples
was required to produce effects equal to those produced by the minimun dose of the standard
ganja.

(b) In the following experiments the dose was increased to 1/110,000 of the body weight:—

                                Experiment No. 38, Satara ganja, No. 1.

Weight of cat 2 lb 111/2 oz. Dose .17 grain at 12 noon. 1 P.M., rocking movements; on
standing up swaying of body from side to side; is somewhat drowsy. 1-15 P.M., spasmodic
attacks of tremor of the head observed; the difficulty in maintaining the body equilibrium on
standing is very marked. 1-30 P.M., asleep; 2-30 P.M., still much affected. 3-30 P.M., sleepy
and torpid. 4 P.M., still under influence of the drug.

                                  Experiment No. 39, Satara ganja, No. 2.

Weight of cat 2 lb 12 oz. Dose .17 grain at 12-40 P.M. 2-30 P.M., rocking move-
ments. 3-40 P.M., drops off to sleep now and again while in the sitting posture; has a "drug-
ged " appearance; is evidently uncomfortable and in distress; body sways from side to side,
displaying the condition termed a difficulty in maintaining the body equilibrium.

                              Experiment No. 40, Ahmednagar ganja, No. 2.

"Weight of cat 3 lb 21/2 oz. Dose .2 grain at 11-40 A.M. 2 P.M., torpid and sleepy;
gait weak. 2-10 P.M., asleep. 2-30 P.M., asleep and when disturbed found to be very unsteady
on its legs. 3-30 P.M., asleep with its nose on the ground.

                                      Experiment No. 41, Bangalore ganja.

Weight of cat 3 lb 123/4 oz. Dose .24 grain at 12 noon. 1-10 P.M., vomited a small
portion of the dose. 2 P.M., asleep with its nose on the ground. 3-30 P.M., on standing up
displays great apparent difficulty in maintaining its equilibrium, the body swaying from side
to side; is very definitely under the influence of the drug.

                                    Experiment No. 42, Madras local market ganja.

Weight of cat 4 lb 11 oz. Dose .29 grain at 12-45 P.M. The effect produced, though
recognizable, not equal to that of the minimum dose of the standard.

                                            Experiment No. 43, Khandesh bhang.

Weight of cat 3 lb 33/4 oz. Dose .2 grain at 12-55 P.M. No appreciable effect.

                                            Experiment No. 44, Amballa bhang.

Weight of cat 4 lb 21/2 oz. Dose .26 grain at 12-10 P.M. No appreciable effect.

                                            Experiment No. 45, Sholapur bhang.

Weight of cat 3 lb 111/2 oz. Dose .23 grain at 11-45 A.M. No appreciable effect.

                                              Experiment No. 46, Satara bhang.

Weight of cat 4 lb 111/4 oz. Dose .29 grain at 12-25 P.M. Effects not appreciable.

                                        Experiment No. 47, Amballa charas, No. 1.

Weight of cat 4 lb 101/2 oz. Dose .29 grain at 1-5 P.M. In this case insufficient effects
were produced.

(c) The twenty-five following experiments were conducted with a dose equivalent to 1/100,000
of the body weight:—

                                        Experiment No. 48, Ghazipur illicit ganja.

Female cat, weight 2 lb 14 oz. Dose .2 grain at 1-45 P.M. Effect nil.

                                            Experiment No. 49, Kistna ganja.

Female white cat, weight 3 lb 71/4 oz. Dose .24 grain at 1-15 P.M. Slight vomiting
occurred after the dose. 3 P.M., asleep with its nose resting on the ground, and on being
disturbed is found to be considerably affected; the rocking movements of the body are well
marked, and on walking the animal staggers from side to side, the hind limbs being most
affected. 4 P.M., is still under the influence of the drug.