REPORT ON THE WORKING OF THE KING INSTITUTE, GUINDY       

9

villages in the Saidapet range should be placed under the immediate
control of the Director of the King Institute as a "model vaccination
range" where the Director with his own trained permanent staff of
vaccinators and Inspectors and with his constant personal supervision
and that of the Assistant Director, can have the efficacy of the vaccine.
lymph turned out by the Institute tested whenever required, and this
work watched and carried out under ideal conditions.

    (j) Yield of pulp.—Statement No. 8 shows the average yield of pulp
per calf during the year under report. The average yield per calf this
year was 22.07 grammes as compared to 23.5 grammes for the year previous.
Most scrupulous care however was exercised and all advanced material
was carefully excluded. The following table shows the average yield per
calf since 1904.

Average for 15 years.
Year. Average yield
per calf
(grammes).
Number of
calves used
per annum.
Year. Average yield
per calf
(grammes).
Number of
calves used
per annum.
1904-1918 4.9 ... 1921-1922 20.2 997
1918-1919 5.31 2,854 1922-1923 20.4 825
1919-1920 7.7 ... 1923-1924 23.5 873
1920-1921 14.6 1,360 1924-1925 99.07 998

    The number of calves actually used for manufacturing the stock
lymph was 998. The large number of calves operated on during the year
was due to two causes:—

    Firstly, to meet the large demands that were made from the various
districts, the number of doses issued being the highest in the records of
this Institute with an excess of 39,490 cases over the figure for the
previous year, and secondly, it was thought advisable to build up a large
reserve stock of lymph in view of the smallpox epidemic prevailing in
Madras and the Presidency, and the increased number of re-vaccinations
done by the Corporation of Madras.

    Besides the above, 223 more calves were used for various experiments
which were carried out in the Institute in connexion with purification
of vaccine lymph.

(ii) BACTERIOLOGICAL SECTION.

    (a) Manufacture of vaccines.—The total number of doses of bacterial
vaccines supplied during the year was 105,497 as compared with 62,521
issued during the year previous showing an increase of 42,976. Statement
No. 9 gives the number of doses of vaccines issued during the last 5 years,
while statement No. 10 shows the various types of vaccines supplied
during the year under review. The increase in the total quantity issued
is due to the larger demand chiefly for the prophylactic cholera, and also
for mixed T.A.B. and influenza vaccines. This increase amounted to 2,669
doses in the case of influenza, 2,073.5 in the case of T.A.B. and 37,751 in
the case of cholera vaccine, and it is most gratifying to note that the
prophylactic vaccines are being largely utilized as a protective measure
against these diseases. The number of doses of anti-meningococcus
vaccine was less than in the previous year, probably because there was no
epidemic of cerebro-spinal fever. The total number of doses of auto-
genous vaccines issued was 3,495 as compared to 3,297, last year's figure,
and shows an increase of 198 doses. The number of returns received
showing the results of treatment with these autogenous vaccines was
again found to be negligible and therefore not of any value for analysis.

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