18

     With the aid of my Hospital Assistant I was able to obtain a two-hour
chart (chart III) of the attack which commenced about the 1st of January.

     The results of blood examinations and the variations in the size of the spleen
were as follows :—

1-11-02     A few Malignant Tertian rings. Spleen 2 inches below the
ribs.
4-11-02     Two Malignant Tertian rings and four crescents after a short
examination.
7-11-02     Many rings, crescents and pigmented leucocytes.
11-11-02     One crescent, no rings, one pigmented leucocyte after a fairly
long examination.
13-11-02     One crescent only; no rings.
15-11-02     A few crescents; no rings. Spleen 2 inches below the ribs.
1-12-02     A few Malignant Tertian rings; a few crescents. Spleen 3 inches
below the ribs.
3-12-02     No rings; two crescents.
15-12-02     Scanty rings and crescents.
19-12-02     One crescent; no rings after long search.
30-12-02     Two rings; no crescents.
2-1-03     A fair number of Malignant Tertian rings; no crescents.
3-1-03     Scanty rings only.
4-1-03     No parasites nor pigment after long search.
5-1-03     Ditto ditto.
6-1-03     12 P.M. A few Malignant Tertian rings.
7-1-03     12 noon. Very scanty rings.
      4 P.M. Very scanty rings.
8 P.M. Only two rings found.
12 P.M. Three rings; one crescent.
8-1-03     4 A.M. One pigmented ring only found.
      12 noon. A fair number of rings.
8 P.M. Two rings only.
9-1-03     6 A.M. A fair number of rings.
11-1-03     One ring only found. Spleen 3 inches below the ribs.
20-1-03     One ring; one crescent.
23-1-03     No parasites nor pigment after long search.
25-1-03     Ditto ditto.
26-1-03     Ditto ditto.
3-2-03     One ring after long search.
11-2-03     One crescent; no rings.
21-2-03     One crescent.
8-3-03     One ring after long search. Spleen 2 inches below the ribs.

     Signs and symptoms; diagnosis by clinical methods.—At the time when the
systematic examinations in November were begun, it was known that this child
had suffered from an entirely untreated infection with Malignant Tertian malarial
parasites for seven months, and from the mother's account it was probable that
the infection had lasted considerably longer than this. if we admit that the