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   Case XX.—Hyapatha garden. January 1908.

     Bengali Babu. Age 20.

        Length of residence in Duars.—5 years.

   History.—No history of previous attacks. Has been ten months at Hyapatha. Three
months ago had " liver " and was yellow in the eyes. He has had enlarged
spleen for one year.

   13th January 1908.—At 11 A.M. had fever with ague and nausea. Did not attend work
after this on account of sickness.

   14th January 1908.—Took three tabloids of quinine, 5 grains each.

   15th January 1908.—Took four tabloids of 5 grains each.

   16th January 1908.—Took two tabloids at 8 a.m. and a dose of spleen mixture at 9 a.m.
At 10 a.m. had ague. At 2-30 p.m. passed dark red urine and continued to pass
urine of a dark ruby red all day.

   Seen by us at 7 p.m. Complains of epigastric pain. Spleen below costal margin. Pulse
full and of high tension. Coagulation of blood markedly increased. Tempera-
ture 104.8.

      Splenic puncture was performed within a few minutes of our anival.

   Blood—

      Coagulation markedly increased.

      Hæmoglobinæmia shown by receiving blood into one per cent. salt and
centrifugalisation.

      Serum separated from clot of an intense orange colour, bands of oxyhæmo-
globin being visible on spectroscopic examination.

Isotonic point—

   Hœmosozic value.—1.12 per cent. salt.

   17th January 1908—Passed hæmoglobinous urine all day.

   Isotonic point.—9 A.M.