201

     Isotonic point.—First definite increased tint at .425. Marked hæmolysis at .4 per
cent. salt.

    Hœmonosozic value.—1.258 %.

  Films taken at 10 A.M., 4 P.M. and 9 P.M. showed no parasites or pigmented leucocytes.

  A count of 500 leucocytes gave:—

Polymorphonuclears .. .. .. .. 73.6%
Large mononuclears .. .. .. .. 20.2%
Small mononuclears .. .. .. .. 6.%
Eosinophiles .. .. .. .. .2%

    Urine.—Hæmoglobinous urine passed all day.

    23rd February 1908.—Urine hæmoglobinous up to 10 A. M. Spleen just below costal
margin. Marked yellow colouration of the conjunctivæ and skin.Anæmia
much more pronounced than yesterday.

    24th February 1908.—Patient convalescent. Temperature 99. Spleen just palpable
Urine free from hæmoglobin.

    25th February 1908.—At night had a rise of temperature to 103.

    27th February 1908.—Given 2½ grains of quinine at 9-30 A.M., 1-30 P.M., and 5-30 P M.

    28th February 1908.—Given 2½ grains of quinine at 2 A.M., 6 A.M., 10-30 A.M., and
2-30 P.M.

   5.P.M., slight rigor.

   5-15 P.M., passed 8 oz. hæmoglobinous urine.

   Hæmoglobinuria continued till 10 P.M. There was a Second rigor at 6-40 P.M. Urine
at 1 A.M. next morning free from hæmoglobin, but temperature remained between 101 and 103
throughout the whole of the 29th and showed an evening rise to 100 on the following two days.

   Estimation of amount of hœmoglobin in urine—

  Time. Urine
Quantity.		 Percent-
age hæmo-
globin.		 Total
hæmoglobin
(blood
equivalent).
22nd February 1908  4 A.M. 312 c.c. 2% 6.25 c.c.
"  7 A.M. to 8-30 A.M. 625 c.c. 3% 18.75 c.c.
" 10 A.M. 284 c.c. 5% 14.2 c.c.
"  1 P.M. to 2 P.M. 570 c.c. 5% 28.5 c.c.
"  3 p.m. to 4-30 P.M. 510 c.c. 3% 15.3 c.c.
"  6 P.M. 285 c.c. 3% 8.5 c.c.
"  7 P.M. to 9-30 P.M. 655 c.c. 3% 19.6 c.c.

227 H D

3E