18     THE INDIAN JOURNAL OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY [ I, I

comes down to normal on the fourth day [Meadows]. The muzzle is generally
quite moist, sometimes with a ropy saliva hanging from the lips and a copious flow of
fluid from the nostril. There is complete suspension of rumination and feeding on
the first day, but these are usually resumed on the second day. " A very constant
and noticeable feature is a swelling around the eyes, which gives the animal a dull,
heavy appearance; in many cases this swelling and severe lachrymation is the
earliest clinical symptom, and with redness of the conjunctiva and glaring appearance
of the eye is most diagnostic" [Bevan]. Constipation is usually present but not
invariable, and there may even be diarrhœa at the commencement; the dung is
usually covered with strings of mucus. According to Bevan, "tympanites is
seldom present", but Edmonds and Walker [1929] mention the occurrence of
" frequent tympanites ".

         Several workers in India have referred to the great suddenness with which the
disease makes its appearance. Thus, Meadows [1919] observes : " An animal
may be left quite all right and found a very few hours later with high fever and
showing all symptoms". Again, Gopal Krishnan [1929] writes: "An animal
apparently quite sound in the morning will be found to be in high fever when it
returns in the evening after work ".

         Venkatachala Iyer [1924], who would appear to have had considerable oppor-
tunities of studying the disease in India, has furnished a brief account of the
disease-syndrome, embodying the essential clinical symptoms exhibited, and his
account will bear quotation as illustrating the remarkable quickness with which the
symptoms follow and the very brief period that elapses between their onset and
final disappearance : " The attack was ushered in with rigors, staring coat, droop-
ing ears and dry muzzle. The animal was off feed and dull, the mucous membrane
congested and the bowels constipated. The temperature was found to be raging
between 103-104° F. [Cf., however, Bevan's and Meadows's observations in this
respect]. A couple of hours after these symptoms commenced there was slight
dribbling of saliva. Respiration and pulse were found to be accelerated. These
indications lasted from one to three days. On the second or third day slight
metastatic lameness appeared. In animals that recovered improvement took
place by the abatement of the symptoms after the third day ". It is of interest
that the occurrence of 'rigor' is also mentioned by Misra [1927] as being an
invariable feature of the disease, for this observer writes : " The animal shivers
as a man does in malaria which is very evident in almost every case". This
phenomenon, however, does not appear to have been recorded by other workers.

         Rabagliati [1924], commenting on Venkatachala Iyer's account as reproduced
above, states, on the authority of Allen [1909], that the symptoms observed in the