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96 THE INDIAN JOURNAL OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY [ III, I

11th day. 100 c.c. of a 1 per cent. solution of tartar emetic intravenously.
16th day. As on the first day.
21st day. As on the sixth day.
26th day. Ditto.
31st day. As on the first day.
(In all, 6 grms. of " Bayer 205 " and 4 grms. of tartar emetic.)

III.—TREATMENT OF EQUINE SURRA BY THE COMBINED INTRAVENOUS-INTRATHECAL
INJECTION OF " BAYER 205 ".

Edwards' [1928] original trials with this method were carried out upon 19
horses (for reasons stated below, Mare No. 68 and Horse No. 70 may be excluded),
and the results obtained by him are summarized in the following Table :—

TABLE II
Treatment by combined intravenous-intrathecal injections.

Serial No	Animal	Data of infective inoculation	Dose of "Bayer 205" in grammes per 1,000 lb. body-weight		Result	Remarks
Serial No	Animal	Data of infective inoculation	Intravenous	Intrathecal	Result	Remarks
1	Horse No. 26	5th Oct. 1925	5.0 Nov. 7th	0.02 Nov. 7th	Cured
2	Horse No. 35	5th Oct. 1925	5.0 Oct. 23rd	0.02 Oct. 23rd	Cured
3	Mare No. 68	4th Sept. 1925	5.0 Sept. 23rd 5.0 Oct. 23rd	0.02 Sept. 23rd 0.02 Oct. 23rd	Cured	Relapsed 14th October 1925. Tryparsamide used for intra- thecal injection.
4	Horse No. 60	4th Sept. 1925	5.0 Sept. 23rd 5.0 Oct. 23rd	0.02 Sept. 23rd 0.02 Oct. 23rd	Cured	Never relapsed between injections.
5	Horse No. 21 A	29th Aug. 1925	5.0 Sept. 23rd 5.0 Oct. 23rd	0.02 Sep. 23rd 0.02 Oct. 23rd	Cured	Ditto.
6	Donkey No. 35	14th Oct. 1925	5.0 Oct. 21st	0.02 Oct. 21st	Cured	Infected intrathecally.
7	Donkey No. 4	20th Oct. 1926	5.0 Oct. 21st	0.02 Oct. 21st	Cured	Ditto. Tryps. not seen in spinal fluid at " the time of drug injection (fluid very blood- tinged).
8	Donkcy No. 36	6th Oct. 1926	5.0 Oct. 14th	0.02 Oct. 14th	Cured	Infected intrathecallv. Tryps. present in spinal fluid up to the day of treatment.
9	Donkey No. 11	20th Oct. 1925	5.0 Oct. 21st	0.02 Oct. 21st	Cured	Infected intrathecally.
10	Donkey No. 17	20th Oct. 1925	5.0 Oct. 21st	0.02 Oct. 21st	Cured	Ditto.
11	Mare No. 57	5th Oct. 1925	5.0 Oct. 26th 5.0 Dec. 21st	0.02 Oct, 26th 0.02 Dec. 21st	Died on 2nd Febru- ary 1926 of suspec- ted chistosomia- sis.	Relapsed about 11th December 1925. Tryps. in spinal fluid on 26th October 1925, but none on 1st February 1926. No parasites in circulation since 21st Decem- ber 1925.
12	Horse No. 28	22nd Sept. 1925	5.0 Nov. 13th 5.0 Dec. 21st	0.02 Nov. 13th 0.02 Dec. 21st	Cured	Relapsed 19th December 1925, with tryps, in circulating blood, but spinal fluid not evi- dently examined on this date. Tryps. in spinal fluid on 13th November 1025.