334 THE INDIAN JOURNAL OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY [VI, IV

of 3.75 grains of the drug (or 1.5 grains per 100 lbs. body-weight)
on six consecutive days. The total quantity of the drug for the whole
course of treatment was 22.5 grains. Daily examination of the
nasal discharge showed that dark and dead ova began to appear
from the fifth day after the commencement of the treatment, and
the ova disappeared from the 12th day. In six weeks the snoring
and the lesions disappeared. The animal improved in condition
progressively and weighed 365 lbs. before it was destroyed on 13th
August 1935. A careful post-mortem examination was held and no
schistosomes could be detected in its nasal veins and the histological
examination of its nasal mucous membrane showed that the lesions
had healed.

Bullock No. 2.—Weight 308 lbs. Age 6 years. Duration of disease one
year. It had small lesions and little snoring. The average number
of ova in 0.1 c.c. of the nasal discharge was 5. It was given 9 grains
of the drug (or 3 grains per 100 lbs. body-weight) repeated every
fourth day and received in all 36 grains in two weeks. In the nasal
discharge of this animal, dark and dead ova began to appear from the
third day after the primary injection and no ova could be seen from
the tenth day onwards. The other symptoms abated in 3 weeks.
This case was cured and weighed 392 lbs. at the end of 5 months.

Bullock No. 3.—Weight 262 lbs. Age 4 years. Duration of disease one
year. It showed ulceration on the tumified nasal mucous membrane
with very little snoring. In the nasal discharge, 38 ova on an aver-
age, were found in 0.1 c.c. It was injected with 12 grains of tartar
emetic per dose (or 4 grains per 100 lbs. body-weight). This animal had
a rise in temperature within 48 hours after the injection (103.8° F.)
and it returned to normal on the sixth day. This dose of the drug
was repeated on the seventh day. Some hours later its tempera-
ture rose up to 105°F. and the animal died 12 hours after the injection.
The cause of death was perhaps due to antimony poisoning. Post-
mortem examination revealed dead schistosomes in the veins of the
nasal mucous membrane and also in the clot of blood found in the
heart. In this animal, from the fourth day after the primary in-
jection, dark and dead ova began to appear in the nasal discharge
and the total number of ova lessened by the sixth day.

Bullock No. 4.—Weight 308 lbs. Age 7 years. Duration of disease 2 years.
It had gross lesions in the nose and snored intensely. About 28 ova
were present in 0.1 c.c. of nasal discharge. This animal was injected
with 15 grains of the drug (or 5 grains per 100 lbs. body-weight).
Within 18 hours after the injection, its temperature rose up to