8                                     Surra.

RESULT OF TREATMENT WITH ATOXYL, MERCURY AND
                            TARTAR EMETIC.

Several of the ponies, immediately after they contracted
Surra, were sent to Muktesar for experimental purposes. Treat-
ment was commenced a few days after the disease had been
diagnosed. The ponies were, as a rule, in poor condition as
they had been doing double their ordinary work for some
weeks.

                                ATOXYL.

The first injections of atoxyl were made subcutaneously,
but these were not rapidly absorbed, and consequently the
intravenous method was adopted. This was also the case
with mercury, which, when injected subcutaneously, was not
absorbed and caused pain and swelling and in one case necrosis
of the subcutaneous tissue. The primary results of the atoxyl
treatment appeared very promising. The animals improved
rapidly in condition and the parasites disappeared from the
blood. But whenever the treatment was stopped and even
during a continuous treatment for a long period, the trypano-
somes re-appeared and the condition of the animals became
worse.

                            ATOXYL ALONE.

Pony 243, height about 14 hands, body-weight 678 lbs.
Disease diagnosed 8th September. Treatment commenced
19th September.

                        Quantity of Atoxyl received.

c.c.

gms.

800

of

2

%

Atoxyl

subcut.

=

16

subcut.

= 16

gms

subcut

290

2

%

intrav.

=

5.8

intrav.

= 39.3

gms.

intrav.

150

4

%

=

6

50

8

%

=

4

50

12

%

=

6

50

15

%

=

7.5

50

20

%

=

10

(Solutions were filtered and heated to blood heat before
injection.)