10                                      Surra.

seems to have been carried direct to the kidneys and set up
acute Nephritis.

A guinea-pig inoculated intraperitoneally with 5 c.c. blood
direct on October 10th, and a rabbit which received a similar
inoculation, showed no symptoms of Surra.

Pony 246.—Height about 14 hands, body-weight 630 lbs.
Disease diagnosed September 17th. Treatment commenced
September 27th.

c.c.

Gms.

300 of 2%

Atoxyl

subcut.

=

6

subcut.

= 6

gms. subcut.

235 „ 2%

intrav.

=

4.7

intrav.

= 58.7

gms. intrav.

400 „ 4%

=

16

400 „ 8%

=

32

50 „ 12%

=

6

                                            Injections.

Date.

Quantity
injected.

Atoxyl sol.

How
injected.

Trypanosoma
present or
absent.

c.c.

September

27th ... ...

100

2%

Subcut.

Numerous.

28th ... ...

100

2%

Absent.

29th ... ...

...

(No injection)

...

30th ... ...

100

2%

Subcut.

October

1st ... ...

35

2%

Intrav.

2nd ... ...

50

2%

3rd ... ...

...

(No injection)

...

4th ... ...

50

2%

Intrav.

5th ... ...

50

2%

6th ... ...

...

(No injection)

...

7th ... ...

50

2%

Intrav.

8th ... ...

50

4%

9th ... ...

50

4%

10th ... ...

50

4%

11th ... ...

50

4%

12th ... ...

...

(No injection)

...

13th ... ...

...

(No injection)

...

14th ... ...

50

4%

Intrav.

15th ... ...

50

4%

16th ... ...

50

4%

17th ... ...

50

4%

18th ... ...

...

(No injection)

...

19th ... ...

20th ... ...

21st ... ...

50

8%

Intrav.

Present.

22nd ... ...

50

8%

Numerous.

23rd ... ...

50

8%

Absent.

24th ... ...

50

8%

25th ... ...

50

8%

26th ... ...

50

8%

27th ... ...

50

8%

28th ... ...

50

8%

Treatment ceased. On November 1st the parasites again
appeared in large numbers in the blood. On the 4th another
intravenous injection of 50 c.c. of a 12 per cent. solution was
given and the trypanosoma disappeared on the following day