14                          Surra.

This injection produced great distress. The animal lay
down and breathing was difficult. The following injections
were not attended with any sign of inconvenience :—

The injections of tartar emetic were continued at the
same dose at intervals till December 12th, until in all 9.2
gms. of tartar emetic had been given intravenously and then
discontinued. The pony improved in condition and the
trypanosoma did not appear in the blood for three weeks after
the treatment was discontinued. On January 4th parasites
again appeared in the bood and the pony was destroyed.

Pony 252—Was treated with atoxyl and tartar emetic
for a period of 6 weeks, receiving—

This pony showed great improvement and the trypanoso-
ma were absent from the blood during the period of treat-
ment. A month after the treatment was discontinued the
parasite reappeared and the animal rapidly grew worse.

Several experimentally inoculated ponies were treated
with other drugs, alone and in combination, such as tartar
emetic and mercury, mercury and methylene blue, methylene
blue and atoxyl, iodoform alone, and mercury alone.

In all cases the injections were given intravenously and
the treatment was continued for about two months. In every
instance, under the early treatment the animal improved in
condition and the trypanosomes disappeared from the blood,
but invariably either towards the latter period of treatment
or some weeks after the injections had been discontinued, the
parasites reappeared and the disease gained the ascendency.
The use of mercury intravenously seemed to have no beneficial