Surra.                                17

In the following ten cases, 3 rabbits, 5 guinea-pigs and 2
ponies, the result of the treatment has been most successful.
With the exception of Pony No. 260, the cases have been under
observation for three months from the commencement of the
treatment, and during this time no trypanosomes have been
found in the blood which was carefully examined daily. All
the animals have improved in condition and appear in com-
plete health.

Guinea-pig No. 270 received one dose of atoxyl and one
dose of orpiment and a week after was inoculated with Surra.
The inoculation was without effect.

Pony No. 271 was inoculated with Surra and on the 6th
day the temperature rose to 39.5°C., and the treatment was
commenced before the trypanosomes were observed in blood.

The Surra used in the experiments was of a very virulent
strain and has infected a very large number of animals with-
out a single negative result.

The solutions of atoxyl were freshly prepared and given
subcutaneously. The orpiment was administered in bolus.

                                  PONY 260.

Body weight
in lbs.

June 25th

... Inoculated with Surra ... ...

... ...

July 1st

... ... ... Tryps, appeared in blood.

254

„ 1st

... 50 c.c. of 4% Atoxyl ... ...

254

„ 3rd

... 0.5 gms, of Orp. „ absent.

240

„ 5th

... 50 c.c. of 4% Atoxyl „ „

240

„ 7th

... 0.5 gms. of Orp. „ „

238

„ 9th

... 50 c.c. of 4% Atoxyl „ „

247

„ 11th

... 0.5 gms. of Orp. „ „

236

„ 13th

... 50 c c. of 4% Atoxyl „ „

236

„ 14th

... Do. „ „

237

„ 16th

... 0.7 gms. of Orp. „ „

242

Aug. 31st

... ... ... „ „

268

This pony has been kept under observation for six
months and remains in good condition and no trypanosomes
have again appeared in the blood.

                                      PONY 271.

Body weight
in lbs.

May 13th

... Inoculated with Surra

......

350

„ 18th

... 50 c.c. of 4% Atoxyl

Tryps. absent.

......

2