Surra.                                 21

In the nine cases, where the disease was in an early stage,
the treatment has apparently effected a cure. Whether an
equally good result can be obtained with animals in a later
phase of the disease has yet to be proved.

A large number of experiments have been made to decide on
the requisite dose of atoxyl.

Animal.

Age.

Body
weight
in lbs.

Injections Subcut.

Quantity
of Atoxyl
in gms.
per 500
lbs.

Result.

Gms.

Gms.

Mare ...

Aged

670

300 c.c. 2% = 6

4.47

Lived. No toxic effect.

Pony ...

420

250 c.c. 2% = 5

5.95

„ „

„ ...

330

200 c.c. 2% = 4

6.06

„ „

„ ...

390

250 c.c. 2% = 5

6.41

„ „

„ ...

460

375 c.c. 2% = 7.5

8.15

„ „

„ ...

2 years

250

250 c.c. 2% = 5

10.0

Colic on 2nd day.
Death on 5th day.

„ ...

Aged

500

500 c.c. 2% = 10

10.0

Lived. No toxic effect.

„ ...

497

559 c.c. 2% = 11.18

11.24

Death on 4th day.

„ ...

220

100 c.c. 5% = 5

11.36

„ „

„ ...

405

500 c.c. 2% = 10

12.34

1 Death with colic in 33
hrs. 40 ms.

„ ...

490

612.5 c.c. 2% = 13.25

13.52

Death following day.

Mare ...

750

1064 c.c. 2% = 21.28

14.18

Death early following
morning.

Animal.

Age.

Body
weight
in lbs.

Injections Intrav.

Quantity
of Atoxyl
per 500
lbs.

Result.

Gms.

Gms.

Pony ...

360

30 c.c. 4% = 1.20

1.66

Lived. No toxic effect.

„ ...

9

283

25 c.c. 4% = 1

1.76

„ „

„ ...

Aged

630

50 c.c. 8% = 4

3.17

„ „

„ ...

Aged

630

50 c.c. 8% = 4

3.17

„ „

„ ...

6

564

50 c.c. 8% = 4

3.54

Lived (stood the dose
on 4 consecutive
days).

„ ...

6

678

50 c.c. 15% = 7.5

5.53

Lived.

„ ...

Aged

574

50 c.c. 15% = 7.5

6.53

Death.

„ ...

8

565

50 c.c. 15% = 7.5

6.63

„ ...

6

678

50 c.c. 20% = 10

7.37