66                                SURRA.

About two hours after the dose of Ars. Ac. solution the
pony had a severe attack of tympanitic colic and died in a
few hours.

The cause of these two fatalities is not known. The
dose of arsenic was not sufficient to cause poisoning, nor did
the symptoms or post-mortem appearances support this view.
The arsenic solution had been made in a large quantity
10,000 c.c. It was several days old. Five other ponies
which received relatively small doses of the same brew of
arsenic solution showed similar symptoms of tympanitis but
recovered on being treated by hypodermic injection of strychnia.
The two cases which succumbed received the usual treatment
with stimulants and carminatives which was of no avail.

            RULES FOR TREATMENT OF SURRA.

The following instructions were issued in September
1909 as a guide to veterinary officers in India who proposed
to apply the arsenic treatment to Surra cases in their
district. As it was pointed out that the preparations and
transport of arsenic solutions would be a difficulty in district
work, the method of treatment with atoxyl and arsenic in
bolus was advised.

                  Rules for Surra Treatment.

I. Solutions of Atoxyl should be freshly prepared
before use in distilled or boiled water. The water should be
allowed to cool before the solution is made. Carbolic Acid
should not be used for sterilizing as it decomposes the
Atoxyl. The solution is to be injected subcutaneously with
the usual aseptic precautions.

The Atoxyl by itself has no curative effect, but ex-
ercises a rapid action in clearing the circulation of mature
trypanosomes . It is, therefore, used only when trypano-
somes are present in the circulation. The use is indicated