SURRA.                                   97

and treatment with large doses cannot be continued for any
length of time. The effect of small doses from 3 grammes to
5 grammes, on the trypanosomes in the circulation is slight.
Full sub-toxic doses have a more marked effect, keeping the
circulation free from parasites from four to five weeks.

(2)  In one case (Camel No. 13), twelve small doses of Arse-
nic appear to have exercised a beneficial effect. The trypano-
somes were absent from the blood from date of treatment to
time of death, 182 days. Death was mainly due to exposure
to rains and want of proper food.

(3)  Arsenic in form of Trisulphide, Atoxyl and Soamin
were tried without success.

20 grammes of Trisulphide proved fatal.

An injection of 10 grammes of Soamin was followed by
death in 24 hours. After 20 grammes the animal died in nine
days and after 30 grammes the camel showed symptoms on the
second day and died after 24 days.

(4)  Arsenic in combination with Tartar Emetic gave no
better result than Arsenic alone.

(5)  Tartar Emetic in single doses is better tolerated than
Arsenic, but the effect on the trypanosomes in the circulation
is not marked. In continuous treatment Tartar Emetic gave
results superior to Arsenic. Camel No. 18 received six doses.
Trypanosomes were absent from the circulation up to time of
death, 196 days. Death was mainly due to exposure and want
of suitable food.

Camel No. 20 was given six doses. Trypanosomes were
absent from the circulation for 118 days.

(6)  A subcutaneous injection of 125 c. c. of a 1% solution
of trypanblau caused necrosis of the skin at seat of inoculation
and had no effect on the trypanosomes in the circulation.

(7)  Subcutaneous injections of Lithium Antimony Tar-
trate caused lesions at the seat of inoculation and had little effect
on the trypanosomes.

                                                                                                   7