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derived from this knowledge; for, those who were reckoned to be
authorities in this field of study could not make up their minds
whether it was best to attack the problem by clearing the forests
which harboured the vector or by stamping out the game believed
to act as reservoirs of the trypanosomes ; in any event, both pro-
positions appeared to be economically quite impracticable. Hence,
short of avoiding the areas in which these diseases were known
to occur nothing seemed to have been done except to exploit
the possibilities of therapeutic treatment. He considered that the
results hitherto recorded in connection with the therapeutic treat-
ment of this group of diseases to be distinctly encouraging. He
had in mind the information recently published concerning the
efficacy of the German preparation "Bayer 205" in the treatment
of human sleeping sickness, and the prospects opened up by the
successes claimed appeared to be so considerable that it had been
put forward that the German Government would hold out the
disclosure of the method of preparation of this compound as the
basis of negotiations for the return of her African tropical posses-
sions. He also mentioned the successes claimed by Dr. Pearce,
of the Rockefeller Institute, with cases of human sleeping sickness
in the Belgian Congo; this worker had kindly placed at his disposal
a quantity of the preparation (tryparsamide) which he employed
for the experimental treatment of surra, but the results hitherto
obtained seemed to indicate that this disease in horses was not
easily amenable to treatment. The results following treatment with
tartar emetic in certain trypanosomiases, such as the surra of
camels investigated by Cross and the trypanosomiasis of cattle in
South Central Africa due to Trypanosoma congolense, were well
known. [At the Muktesar laboratory he had obtained remarkably
good results in the treatment of bovines affected with trypa-
nosomiasis, caused by a trypanosoma indistinguishable from
that of surra, by intravenous injections of tartar emetic]
Spirochætal affections, which might be regarded as nearly related,
had proved often to be most susceptible to chemotherapeutic
treatment. A large amount of information was now scattered in
the literature upon the chemotherapeutic treatment of this class
of disease, and it seemed that a co-ordinated effort should
now be made to ascertain the efficacy of the various classes of
drugs, believed to act as remedies, upon a large scale upon
naturally infected cases in the field. In the case of the domesti-
cated animals susceptible to surra any system of treatment
ultimately recommended must be efficacious, cheap, and easily
applicable. He therefore proposed to seek the co-operation of the
Veterinary Service in the field to the largest possible extent for the
observation of the effects of certain remedies which suggested