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ecchymosis; these changes also exist in the interstitial connective
tissue of muscles in the perinervous and perivascular tissues. The meat
will then present special characters when the animal has succumbed to
the malady. The articular synovial membranes and the tendinous ones
have a wine-coloured, brownish, uniform or spotted hue, and contain a
sanguinolent serosity.

The muscles are sometimes little or not at all altered, but in those
animals which have died of the disease they are profoundly changed,
softened, their fibres altered, some having undergone colloid or granu-
lar degeneration. Certain oviform bodies which are regarded as the
ova of entozoa are sometimes met with in the muscular fibres, but
their real nature has not been yet satisfactorily decided. In the sub-
stance of the muscle we may meet with ecchymoses, red-yellow colour,
brown or black patches, more particularly in the muscular interstices.
None of the above diverse changes have any real pathognomonic
value. The true lesions are those met with in the digestive apparatus;
these are numerous, occurring from the mouth of the anus or through-
out the whole of the digestive tract. We find a very intense state of
congestion and an uniform or patchy coloration which is particularly
well marked in the abomasum, in the neighbourhood of the pylorus,
and in the small intestine. Everywhere the infiltration is very abundant.
The catarrhal and the inflammatory state evince themselves by a
hypersecretion of muco-purulent matter, accompanied by swelling
and desquamation of epithelium, so that the granular degeneration of
the cellular elements is brought about by the exosmotic movements
or results from the cellular proliferation. In the mouth we find very
characteristic lesions in Europe. The lips are always swollen more or
less; their connective tissue is infiltrated. The tongue is hypertro-
phied ; the buccal membrane is swollen. The mouth exhales a fœtid
odour and contains a thick, viscid, very sticky muco purulent, fœtid
saliva, rich in degenerated epithelial cellules, in embryonic elements
and pus cells. The epithelium is swollen, thickened and softened ; it
is easily detached, and is desquamated more or less profoundly in
certain more or less numerous places; it detaches itself in some regions
such as the pad, lips, internal surface of the cheeks, inferior face of
the tongue, etc., under the form of pellicles or plaques or of yellow or
grey grains, a number of which are present in the saliva. The points
from which the epithelium has been detached are the seat of intense
congestion, from which results an exudation which raises the epidermis
and causes it to become detached. In fact the points at which conges-
tion has left the derm bare look congested, brownish or black in colour,
and sometimes, but rarely, the points are transformed into ulcerated
wounds. The derm of the mucous membrane is first changed, even
before the epithelium becomes so; it is much congested, and if the red